For our customer we are looking for a Principal Scientist (m/f/d) (Biomarker Development) to support us in Basel.
Responsibilities
Develop and validate fit-for-purpose cellular biomarker solutions
Independently design, execute, and interpret experiments
Ensure high quality and timely delivery of internal and external results
Providing subject matter expertise for transferring, implementation and monitoring of Flow Cytometry assay development, validation and sample analysis at external provider
Development and validation of cellular biomarker assays based on Flow Cytometry technology
Implementation of validated biomarker assays in clinical studies
Generate and interpret data to enable proof of mechanism, dose selection & proof of biology across early clinical programs and present results at internal meetings
Providing subject matter expertise to transition, implement and monitor assay development and validation at CROs
Empowered for experimental design, execution, interpretation and reporting (oral and written) of assigned projects under unbossed culture
Contributing to write quality reports and laboratory manuals
Cross training on a variety of biomarker modalities and technologies
Requirements
BS/MS degree in Biology, Immunology, Cell biology or a laboratory technician with experience in the pharmaceutical or biotechnology environment
Extensive understanding, knowledge and practical experience in Flow Cytometry, having hands on experience in high dimensional Flow Cytometry would be a plus
Analytical thinking, willingness to accept responsibility, and teamwork skills
Experience working in a global organization and matrix-resourcing model
Good Computer skills (Excel, Word, PowerPoint, Spotfire, GraphPad Prism)
Good communication skills for oral and written in English
Understanding of regulatory requirement relevant to Biomarker Development (e.g. GCLP, ICH)
Benefits
5 weeks holiday / 40h week
Assumption of certification costs
Reka-Card with a 20% discount on up to CHF 2,400
Up to CHF 400 contribution to fitness subscription