For our client, an international pharma company based in Basel, we are looking for a Principal Associate in Drug Delivery and Preformulation Sciences.
The position is located in Preclinical Chemistry, Manufacturing and Controls (pCMC), a department within the pRED Therapeutics Modalities organization, where we pave the path to bring drug candidates from early research into development in a diverse, ambitious and innovative environment. We collaborate actively with our discovery and development partner functions providing cutting-edge technologies and scientific excellence to transform molecules into future medicines. Our team ?Drug Delivery and Preformulation Sciences? is involved in all phases of a project across the value chain from project idea until launch providing pre-formulation know-how and sound scientific expertise in the pharmaceutical profiling of new drug candidates and drug delivery.
General Information: - Start date: ASAP - Latest Start Date: Nov 1st , 2023 - Planned duration: Oct 31, 2025 - Extension: possible - Workplace: Basel - Workload: 100% - Home Office: up to 20% in alignment with line manager - Team: ca. 20 people - Working hours: Standard
Tasks & Responsibilities: - Physical and chemical characterization of new chemical entities (synthetic molecules and peptides) by using analytical tools like DSC, TGA, polarization microscope, DVS - Performing UPLC analytics incl. method development - Determination of solubility and stability according to established best practices - Formulation development and supplies for peroral and parenteral preclinical studies - Documentation in eLN - Self-reliant lab and work organisation, direct exchange and interaction with internal team members and cross-departmental customers in Medicinal Chemistry, Pharmacology and DMPK/Tox
Must Haves: - Apprenticeship or Bachelor or Master in Pharmaceutics or Analytics - Min. 3 years of experience in Preformulation, Analytics and/or Formulation Development as associate or (junior) scientist - Good understanding of pharmaceutically relevant excipients and various dosage forms like solutions, suspensions, emulsions, polymer stabilized amorphous systems - Background in chromatography (UPLC), formulation development, sound scientific lab practices, clean, tidy and accurate work - Advanced English skills - Google platforms, Microsoft Office skills - Team player, advanced communication skills not only with peers, but also with internal and external stakeholders, well organized, self-reliant, flexible, passionate, positive attitude
Nice to Have: - Language: German - IT: Empower, confident to learn on eLNs (e,g, IDBS) - Interest in Digitalization and Automation - Experience in advanced Drug Delivery Technologies Temporary